Test: Viral Hepatitis and Zoonoses

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Test your knowledge of hepatitis and zoonotic infections. Solve the following test where only one answer is correct and send the answers by the given e-mail. Before making of the test study Issue 8 Viral hepatitis and liver infection and Issue 15 Adenopathy, infectious mononucleosis, and zoonoses.

1. We know 7 types of viral hepatitis. Some of their agents are not hepatotropic:
   a. in F and G
   b. in D and E
   
   
2. The patient with acute hepatitis A has positive antibody in serum:
   a. anti-HAV IgG
   b. anti-HAV IgM
   
   
3. The patient suffered from hepatitis A in the past and now he is again infected with viral hepatitis A:
   a. new infection of hepatitis A may occur
   b. new infection of hepatitis A does not occur
   
   
4. Immunocompetent patients can be vaccinated against A hepatitis with:
   a. one dose of vaccine
   b. two doses of vaccine
   c. three doses of vaccine
   
   
5. The patient has acute hepatitis B. The positivity of the which of the following markers in serum was detected:
   a. HBsAg, HBeAg and anti-HBc IgM
   b. HBsAg, HBeAg and HBcAg
   
   
6. Immunocompetent patients are vaccinated against hepatitis B with:
   a. one dose of vaccine
   b. two doses of vaccine
   c. three doses of vaccine
   
   
7. Patient suffered from hepatitis B in the past and now is infected with hepatitis B:
   a. new hepatitis B infection may occur
   b. new hepatitis B infection does not appear
   
   
8. Patient with HBeAg positive chronic hepatitis B has these markers positive:
   a. HBsAg, HBcAg and anti-HBe
   b. HBsAg, HBeAg and anti-HBc IgM
   c. HBsAg, HBeAg and anti-HBc IgG
   
   
9. Patient with HBeAg negative chronic hepatitis B has these markers positive:
   a. HBsAg, HBcAg and anti-HBe
   b. HBsAg, anti-HBe and anti-HBc IgG
   c. HBsAg, HBeAg and anti-HBc IgM
   
   
10. In acute viral hepatitis C we detect in serum:
    a. positivity of antibody anti-HCV IgM
    b. positivity of antibody anti-HCV
    
    
11. Chronicity in viral hepatisis is when infection persists at least:
    a. 3 months
    b. 6 months
    c. 12 months
    
    
12. Into chronicity may evolve:
    a. acute hepatitis B and C
    b. acute hepatitis B, C and D
    c. acute hepatitis B, C, D and E
    
    
13. In severe course of acute hepatitis B can be applied:
    a. pegylated interferon alfa
    b. nucleosid or nucleotid analogue
    c. DAA (direct-acting antiviral) drugs
    
    
14. The patient had hepatitis C in the past. If infected with hepatitis C virus now (e.g. i.v. drug user, when he shares needles and syringes)
    a. new infection with hepatitis C virus may occur (new acute hepatitis C)
    b. new acute hepatitis C does not appear
    
    
15. Chronic hepatitis C is treated with:
    a. pegylated interferon alpha with or without ribavirin
    b. ribavirin
    c. DAA (direct-acting antiviral) drugs
    
    
16. Severe course of hepatitis E can be treated with:
    a. ribavirin
    b. entecavir
    c. tenofovir
    
    
17. Patient suffered from hepatitis E in the past and if he is infected again by hepatitis E virus in the future:
    a. new infection of hepatitis E virus may occur (new acute hepatitis E)
    b. new infection of acute hepatitis E does not occur
    
    
18. If antibodies against Lyme disease in serum were proved, the patient will be treated:
    a. always
    b. only if clinical symptomatology is present
    
    
19. Production of antibodies of the class IgM in Lyme disease usually starts three to four weeks after primary infection, i.e. in the first stage (i.e. erythema migrans) but antibodies should not have been produced yet. In case we are sure that it is erythema migrans, the treatment:
    a. is started
    b. we wait with the treatment till the positivity of antibodies of the class IgM is confirmed
    
    
20. In tularemia specific antibodies appear at the end of the 2nd to mostly 3rd week. If we are convinced that it is tularemia, the treatment:
    a. must be started, because in case of late application of antibiotics, there is a danger of disease progression and need for surgery
    b. treatment should be started after confirmation of seropositivity
    
    
21. Toxoplasma gondii may cause damage to the foetus. It is dangerous if mother during her pregnancy has:
    a. exacerbation of chronic toxoplasmosis
    b. primary infection
    
    
22. If a pregnant woman is not sure whether she had toxoplasmosis in the past, it is useful to examine the avidity of IgG antibodies. Low values are recorded:
    a. in reactivation of chronic toxoplasmosis
    b. in primary infection

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Instruction

• Send the answers of the test on the given e-mail.